Josh W

Josh W

Unopened Gifts

I love birthdays…and holidays…and random Tuesdays…and any day that I can give gifts to people whom I love.  The point of giving is not to experience personal blessings…but it’s an ancillary benefit that accompanies unselfish motivations.  And when that person…

Do Hard Things

“Hard times create strong men.  Strong men create good times.  Good times create weak men. And, weak men create hard times.” -G. Michael Hopf, Those Who Remain We live in an interesting era in which people will spend more time…

Artificial Sweeteners and Spiritual Satiety

Healthcare professionals in metabolic clinics have all been subject to the ironic situations in which people with type 2 diabetes INSIST that drinking Diet Soda will instantly kill them and simultaneously plunge the world into nuclear conflict.  Meanwhile, their Continuous…

Happy Mother’s Day!

This picture was taken about 30 years ago…I was just emerging from my blonde bowl-cut era and preparing to embark on a new journey of Maximum Hold Hair Gel.  But despite my questionable haircut preferences, I wouldn’t have traded my…

Sneaky SNX17, PCSK9, and the LDL Receptor-NERD ALERT!

The punch line to the joke, “Why did the PCSK9 inhibitor not work?” is usually, “Because the patient never took it!” But occasionally, people will get a less-than-expected response in LDL-C lowering to PCSK9 inhibitors.  This is quite unusual, but…

Nurse and Teacher Appreciation Week!

This week we celebrate two criminally underappreciated groups for whom I have special affection.  It’s Nurse Appreciation Week AND Teacher Appreciation Week!  One of the smartest things I ever did was marry a nurse, and both of my parents are…

PCSK9 in the Heart Muscle? Lipid Deep Dive-NERD ALERT!

PCSK9 is well-known for its role in cholesterol homeostasis, and most are aware that PCSK9 targets the LDL receptor for lysosomal degradation.  Given that the LDL receptor in the liver is what clears the majority of ApoB cholesterol-laden particles from…

Everyone is Older, But No One is Wiser

My daughter slumped into the back seat of the car after what had apparently been a particularly tough Tuesday at school. Given that her body language carries the same degree of subtlety as a Level 5 Hurricane, it was obvious…