Category Lipids

“I Never Saw It Coming”

I’m currently on a work trip in Eastern Idaho, but my wife keeps me updated on important life events and noteworthy headlines. And she sent me a news article about a guy with a machete tattoo on his face who…

Useful Biomarker or Click Bait? A Deep Dive into TMAO

Every now and then the topic of trimethylamine N-oxide, or TMAO, is extracted from its watery grave by some “cardiovascular expert” in efforts to convince us that this is something to worry about.  So here’s the rundown on TMAO…get ready…

Got Quack? Get a CAC!

Since Captain Planet is unlikely to be the hero we need for saving the world from Heart Disease (as we learned from last week’s post), perhaps we ought to turn our attention to another early 1990s classic cartoon character…Darkwing Duck!…

Low Albumin, High Cholesterol! NERD ALERT!

Although the well-known autosomal dominant gene mutations for Familial Hypercholesterolemia are LDLR, APOB, and PCSK9, there are lesser-known recessive mutations that can result in elevated cholesterol levels.  One of these recessive gene mutations is LDLRAP1, but THIS ARTICLE describes a…

Metformin Mechanistic Mysteries: NERD ALERT!

France has contributed many luminaries to science, including Pascal and Descartes, but maybe Metformin, a glucose-lowering medication taken by millions of people, deserves a place on this proverbial intellectual Mont Blanc as well.  Derived from the French lilac, Metformin continues…

Artificial Sweeteners and Spiritual Satiety

Healthcare professionals in metabolic clinics have all been subject to the ironic situations in which people with type 2 diabetes INSIST that drinking Diet Soda will instantly kill them and simultaneously plunge the world into nuclear conflict.  Meanwhile, their Continuous…