It’s tricky With drug design To stop the PCSK9 It’s tricky! (Tricky, tricky, tricky)! –Rumored Lipid Remix of Run DMC’s iconic hit “It’s Tricky” Unpublished data suggests that Lipid Learning is enhanced when disseminated in hip-hop format, and I’ve been…
I love anniversaries, and recently my wife and I celebrated our 13th Wedding Anniversary! And that pretty much takes care of the Life and Love parts of this website. But for the “Lipids” section, we can celebrate the 20th Anniversary…
Today’s big news in Lipid Land is that the first oral PCSK9 inhibitor was approved by the FDA! The generic name of this agent, which mechanistically is a macrocyclic peptide, is enlicitide, and I prefer to stick with that since…
The initial CAUGHT-CAD Trial results basically reinforced the “Got Plaque? Get a CAC!” approach to identifying coronary disease and intervening BEFORE the plaque becomes problematic. People aged 40 to 70 with a family history of premature cardiovascular disease underwent testing…
Historically, I haven’t been too enthused about CoQ10 as a supplement given the underwhelming trials and mixed results in abrogating drug-associated muscle symptoms in those on statins. I think creatine supplementation is a much more compelling option, and I think…
This new WNBA meme is too good NOT to use for bringing awareness to Cardiovascular Disease screening and prevention! And most people are comfortable using CACs as “The Colonoscopy of the Heart Without the Nasty Pregame Show” as a screening…
Rats have been responsible for various plagues and pestilences throughout human history, and given their fecundity and ubiquity, they are nowhere near the Endangered Species list…except for one place on the planet: the Canadian province of Alberta. But it’s not…
Writing a book results in some hilariously awkward social interactions. For example, a random person will say, “Hey, I bought your book a while ago!” At this point, I reach into my Grab Bag of Superficial Small Talk options, which…
I’ve previously written about APOC3, the “Great Inhibitor” of lipoprotein lipase (LPL) HERE as well as the Hot Mess of the ANGPTL family HERE, so before you take the plunge into this topic, I’d recommend checking out those articles! Basically,…
“Age is merely a number” –Common statement from your Medspa member friend who spends thousands of dollars every month on Botox and dermal fillers As someone who is the regular recipient of various hedged compliments with the qualifier “for your…
